Such a model can be of value because it (1) allows a variety of viewpoints to be considered, (2) incorporates the best scientific evidence, and (3) permits sensitivity analyses to evaluate the impact of alternative clinical scenarios and uncertainty in model inputs.
Demographical, epidemiological, risk factor and clinical data collected at enrolment in combination with weekly cough persistence data will permit sensitivity analyses to assess the impact of this bias on study outcomes.
The size of the database also permitted numerous sensitivity analyses on subpopulations.
The design tool enabled all key design parameters, with the exception of particle size and orientation, to be varied systematically to permit the sensitivity of the optical properties of the selective absorber coating to be studied.
Bioeconomic modelling constitutes a useful tool in comparing treatment and reuse options, permitting the sensitivity of financial returns to changing costs and recent revisions to WHO guidelines for safe wastewater reuse to be assessed, however, social and environmental consequences demand consideration.
Consequently, for the present, we consider the existence of both LDH-M and LDH-H isoforms in neuronal mitochondria to permit both sensitivity and metabolic flexibility of shuttling in response to changing lactate levels.
In these assays, we measured the activity of FVII toward its physiologic substrate, factor X (FX), by exploiting a fluorogenic substrate for activated FX, which permits high sensitivity to very low activity levels [2,14].
As a result of this increased path length, the high [OH] detection sensitivity permitted unambiguous analyses for measuring the title rate constants.
Moreover, modeling both HSC BrdU uptake and dilution in three stages and careful treatment of the BrdU detection sensitivity permitted improved estimates of HSC turnover rates.
