Sentence examples for permits the activation of from inspiring English sources

Tsuboi [ 44] suggests that it permits the activation of the integrin during the platelet aggregation.

These results are consistent with previous results of the same authors (Rosado et al., 2000; Rosado et al., 2004a) demonstrating that submembrane cortical actin network acts as a clamp that blocks interaction between DTS and acidic Ca2+ stores and plasma membrane and therefore reorganization of submembrane F-actin network permits the activation of Ca2+ entry.

It is thus reasonable to propose that the MSU-induced downregulation of MICL expression releases the inhibitory activity of this receptor in neutrophils permitting the activation of the neutrophil by this nonmicrobial agent.

Like caspases, activated PARP is self-cleaved into 2 subunits, permitting the activation of PARP to be identified.

Due to the delay in the docking of Kristall, EO-6 was extended by 10 days to permit the activation of the module's systems and to accommodate the EVA to repair the loose thermal blankets on Soyuz TM-9.

Cyclin E-CDK2 completes Rb phosphorylation, further permitting the activation of E2F-responsive genes.

Recently, it was also demonstrated to have a pro-survival function in MM by permitting the activation of the non-canonical NFκB pathway.

This could allow the tryptophan levels to increase, permitting the activation of the kynurenine pathway and generating the associated cascade of catabolites capable of enhancing the inflammatory reaction and producing neurotoxicity.

Thus, the significant decrease in XIAP level in MCF-7 cells by S. cripus extracts had permitted the activation of procaspase 9 and effector caspases and therefore execution of apoptosis.

As the repressive H3K27me3 mark can be heritably transmitted to daughter cells to maintain specific gene expression programs (Hansen et al, 2008), expression of developmentally regulated genes would require the removal of the H3K27me3 mark to permit the activation of gene expression.

In the context of cancer, it is important to note that, in the presence of activated H-Ras or N-Ras oncogenes, an active degradation of p300 is induced [54], and this change will permit the activation and subsequent degradation of VRK1 by the new complexes of p53.