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Many RNA viruses such as HIV use a specialized enzyme called reverse transcriptase that permits replication of the virus through a DNA intermediate.
If it only permits replication requests from faculty at a small set of elite schools, requires that faculty submit on behalf of their students, requires that faculty continually review and certify oversight of the replication efforts of their students or bars replication requests from non-academic researchers, that would pose grave challenges to the replication pipeline.
As an example shown in Figure 4, we investigated the kinetics of γH2AX foci as a general DNA damage marker in the response of wild-type MEFs to DNA polymerase inhibitor, aphidicolin (Aph), at 200 nM, a concentration that permits replication at a reduced rate.
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Finally, published scientific papers must permit replication more readily.
The evaluations are achieved in two independent rounds in 1995 and in 2001, permitting replication of our study.
This paper (again apparently unpublished except on his website) explained the lack of scientific support for his claims as follows: Holistic management does not permit replication.
Y family polymerases must be tightly regulated to prevent aberrant mutations on undamaged DNA while permitting replication only under conditions of DNA damage.
The effectiveness of adolescent substance abuse treatment has been repeatedly demonstrated, but specific treatment approaches have rarely been sufficiently documented to permit replication.
That said, in response to controversies over mistakes, coding disputes and academics under siege who are protective of their data, some top journals like The American Economic Review now require authors to submit data and code "sufficient to permit replication" when sending in a paper.
Methods need to be reported in sufficient detail to permit replication of the study.
Methods should be reported in sufficient detail to permit replication (which may require that they be published separately).
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