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Because the quality of the explanted heart tissue did not permit us to conduct the study using cardiac material, we used fibroblasts from the same E161K individual as a surrogate.
These additions to the model would permit us to conduct effectiveness and cost-effectiveness analyses to evaluate various screening and management strategies for EAC prevention.
For studies reporting outcomes only for participants who completed the trial or followed the protocol, we will request the additional information that would permit us to conduct intention-to-treat analyses.
Here, we focused on segmental duplications between chromosome 11 and 12 only because the finished sequences of these chromosomes permit us to conduct an analysis of the organization of their genes in a detail that was not possible before.
Because of the personal and property related security issues in Douala, household owners did not permit us to conduct indoor HLC; this prompted us to adjust the study design, whereby HLC was conducted exclusively outdoors while CDC LT continued to be placed indoors.
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Rejection of the null hypothesis, which predicted a homogeneous distribution of all species on both slopes by the chi-square test (X2 = 5, p = 0.0003), permitted us to conduct individual tests.
The Sorachi Forest Management Office permitted us to conduct our field survey within its boundary.
The two cut-off scores are chosen because they yielded the most conservative estimates and permitted us to conduct logistic regression.
In the event between-study heterogeneity precludes a meta-analysis, or only permits us to conduct a meta-analysis on a subset of studies, we will undertake a narrative synthesis 24 of all of the included studies.
The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1472-6963/14/65/prepub wouldulikeike to thank the health workers who accepted to participate in this study; the District Health Officers for permitting us to conduct this study and John Kirungi for helping to coordinate the study in Masindi.
The D12A/D66A mutant lacks two of the ligands for the catalytic Me2+ ions in the exonuclease active site and thus has negligible exonucleolytic activity, permitting us to conduct experiments under conditions in which DNA substrates bearing 3′-OH termini would be degraded if the wild-type enzyme was used.
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