Thus, when kinetochores come under tension and chromosomes biorient on mitotic or meiotic spindles, the SAC is turned off and Cdk1 is permitted to activate APC/CCdc20 and thereby trigger its own demise as well as separase activation.
During cell stress, Keap1, a cysteine-rich protein sensitive to oxidants/electrophiles, is modified on one or more of its functional cysteines (e.g., Cys, Cys, and Cys), releasing the sequestered Nrf2 and permitting Nrf2 to activate its target genes (Taguchi et al., 2011).
In the absence of copper, Mac1 transcriptionally induces genes involved in copper import, including cell surface metal reductases Fre1 and Fre7 and copper transporters Ctr1 and Ctr3, whereas excess copper permits Ace1 to activate expression of copper-sequestering metallothioneins Cup1 and Crs5 (Zhu et al. 1998; De Freitas et al. 2004; van Bakel et al. 2005; Rustici et al. 2007).
Title 23 of WTO permits the Congress to activate the Secretary of Commerce's list of items necessary to our national security so that a nation can be assured of domestic production and supply.
According to this view (S-S theory), associations are formed between internal representation of the CS and that of the US, and the growth of this association permits the CS to activate a representation of the US in the absence of the US itself.
Bluejeans' liquor license is set to activate once all city clearances — including a permit for sidewalk dining — are complete, said Brad Beach, district director of the Department of Alcoholic Beverage Control office in Van Nuys.
"They did enough to activate the permit," he said.
It may be that a genetic variation permits misoprostol, a PGE1 analogue, to activate the endogenous fever mechanism that is typically triggered by PGE2.
And that proved important when he went back to the Coastal Commission two years later to activate his development permit.
(To activate: scroll, select, click).
Time to activate the PODs.
