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We determined their DNA sequences from both the 5'- and the 3'-ends to permit the functional annotation of the Thellungiella full-length cDNAs, and we discuss their predicted functions related to abiotic stress tolerance.
GO annotation strategies also permit the functional annotation of candidate genes that were uniquely downregulated in pancreatic cancer.
Such techniques permit the functional aspects of tumour neovascularity to be assessed in vivo in a non-invasive and repeatable way.
With the combined efforts of multiple laboratories, it would be possible to generate all of the mutants in a few years, and permit the functional dissection of individual genes in clean genetic knockout background.
Together these findings indicate that Xi reporter systems permit the functional analysis of gene silencing, and that in addition to DNA methylation various other mechanisms contribute to Xi silencing.
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Neurogenesis-induced rewiring occurs in a manner that permits the functional integration of new neurons while maintaining a balance of activity by recruiting inhibitory interneuron networks in the case of the DG, or by directly modulating sensory input and principal neuron output in the case of the OB.
The development and characterization of M-CyldΔ9 mice permitted the functional evaluation of CYLD in the myelomonocytic lineage and revealed an anti-inflammatory element of the functional profile of this molecule.
Furthermore, full-length cDNAs are easy to use with gene transfer systems, permitting the functional analysis of individual genes through reverse-genetics approaches.
Mutually exclusive receptor expression permits the functional specialization of individual sensory neurons in both systems; i.e., individual sensory neurons in both the main nose/VNO are specialized for the odorant-binding functions of the receptor allele expressed in that cell.
More crucially, a complete aurochs genome sequence will permit the identification of functional genetic differences between the B. taurus and B. primigenius lineages, especially those pertaining to agro-economic production traits that have been under intense selection, since the initial founding of domestic herds some 10,000 years ago.
Further development of such approaches will permit the high-throughput functional characterization of regulatory elements and nucleotide variants within them.
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CEO of Professional Science Editing for Scientists @ prosciediting.com