Although sites were permitted some flexibility to include questions of local interest only, the core part of the structured questionnaire comprised questions to be asked at all study sites.
Because our aim was to show that MBCT is an effective augmentation strategy and because we wanted trial results to be widely generalizable in light of routine clinical practice, we permitted some flexibility in medication changes.
However, the algorithmic approach permits some flexibility in the selection and implementation of treatment components to ensure that treatment is relevant and specific for as many participants as possible.
Notably, in a recent study, even though the algorithm used to predict TF dimers permitted some flexibility in the spacing, all of the experimentally validated dimers turned out to be rigid, i.e. they bound with high affinity only at a single motif spacing [ 12].
This is a format that is maintained by an international organization that allows essentially the same sorts of formatting as HTML: bold, italics, etc, and allows the user to resize the font with which he or she is reading, but also permits some flexibility in formatting paragraphs and margins and so forth, which makes for a better-looking page on the screen.
Hence, the immobilisation of Mutant 3 is not as rigid as that of Mutant 1, permitting some protein flexibility.
All told, although the players have clearly made concessions, the rules still permit reasonable flexibility.
Perhaps most symbolic of all, the 75% top tax rate, set up initially as a temporary two-year measure, will be quietly allowed to die.At the same time, the government wants to permit greater flexibility in order to boost competition.
The Obama administration will bring to the table lofty goals: an agreement on curbing the global economic imbalances — too much spending, borrowing and importing by some nations and too little by others — as well as a hope that China will permit greater flexibility in the value of its currency, the renminbi.
