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Only three of the methods under investigation (KOG, OrthoMCL, TribeMCL) permit clustering proteins from multiple species, rather than simply making pairwise predictions for proteins from two species.
The GO categories identified for each gene were made comparable by converting each GO term to the same level in the hierarchy to permit clustering into GOslim categories.
Since gene expression patterns permit clustering of patients with autoimmune disease from normal control subjects, there has been significant interest in using the gene expression data to classify disease subsets and predict responses to treatments.
Thus, we might not have found a R. culicivorax orthologue for a specific gene for three reasons: it may have arisen in the branch leading to C. elegans; its sequence divergence may be too great to permit clustering with potential homologs; or it was not assembled in the draft dorylaim genomes.
Among methods that permit clustering of ortholog groups spanning multiple genomes, the (automated) OrthoMCL algorithm exhibits better within-group consistency with respect to protein function and domain architecture than the (manually curated) KOG database, and the homolog clustering algorithm TribeMCL as well.
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The regulations that would permit cluster-style development in principle were approved last year by the Woodbury Zoning Commission, in response to the developers' plan.
The City Council amended the zoning ordinances in 1983 to permit cluster development in some areas, Mr. Kissinger said, so most of the 563 units approved for construction in 1984 through 1986 were for cluster complexes.
Simultaneously, whole-genome analyses permitted clustering and classification of all phages, with completely sequenced genomes, belonging to the Podoviridae.
Availability of DIRS data permitted clustering of IgG-VHs into groups of clonally related sequences that were derived exclusively from CSF, exclusively from PB, or from both compartments.
BLSOM could recognize and visualize species-specific characteristics of codon or oligonucleotide frequencies in individual genomes, permitting clustering of genes or genome fragments according to species without the need for species information during BLSOM learning.
The BLSOM recognizes species-specific characteristics of codon or oligonucleotide composition, permitting clustering (self-organization) of genes and genomic sequences according to species without the need for species information during BLSOM calculation.
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