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Uses of Nicaraguan Sign Language, Morse Code, and my repetition of words I overhear from another language but do not understand all count as utterances on this permissive criterion.
This could be partially the case in the coregulations established by IHF, FNR and NarL (these hubs shared 8 coregulated operons), and only under a permissive criterion (inheritance of binding sites imposes more strict constrains to the location of homolog genes in their respective operons [36]).
On the other hand, we do not expect protection from such a permissive criterion.
Using a conditional false-discovery rate (cFDR) of 0.01 (permissive criterion for differential expression), EBarrays [ 18] detects over 2204 differentially expressed genes in D. dadantii (48.5%), and 599 in P. atrosepticum (13.4%).
Clinical remission according to definitions 1 and 2 showed similar strength of association with mortality, while the more permissive criterion did not show statistically significant association to the outcome (adjHR 0.82 (95% CI 0.64 to 1.03)).
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I initially used relatively permissive criteria to define blocks: a minimum length of eight residues, with an average entropy of 0.4, at most two gaps of length one, and at most two sites with an entropy > 0.2.
We used more permissive criteria (no fold-effect requirement, but P < 0.01), so as to capture genes and pathways that demonstrated smaller but significant changes in expression.
The first step toward identifying likely SNPs and designing SNP assays was to identify flanking variants (SNPs and indels) using permissive criteria.
Conversely, if too permissive criteria are chosen, patients with significant disease activity may be classified as being in remission and thus miss adequate treatment.
In these cases, the use of permissive criteria to assess the significance of the similarity between proteins can easily lead to wrong annotations.
As expected, the proportion of regularly attending patients, as well as that of adequately treated patients, decreases as less permissive criteria were adopted.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com