Sham surgery had no significant effect on peripheral thresholds at 2 weeks recovery.
The effects of different treatments on CAP peripheral thresholds are illustrated in Figure 1.
We investigated the effects of three treatments (sham, acoustic trauma and mechanical trauma) on peripheral thresholds and measured gene expression in the paraflocculus by RT-PCR.
It has been established that dynamic mechanical allodynia is mediated by peripheral low threshold, large myelinated Aβ-fibers [ 22].
Additionally, viremia levels of all crows injected with NY99 surpassed this level, which suggests that once a peripheral circulatory threshold titer is achieved, virus is capable of accessing the nervous system through a nonspecific mechanism.
This case series reports sustained reversal of the loss of DNIC response in patients undergoing ONS for intractable headache whilst having no effect on peripheral pain thresholds.
Furthermore, we could not replicate the general finding that peripheral pain thresholds are lower in headache patients as compared to healthy control subjects [13].
It is established that dynamic mechanical allodynia is mediated by peripheral low-threshold, large myelinated Aβ-fibers [7] [9].
Baseline peripheral sensory thresholds were measured at pre-marked testing sites along the medial aspects (liver and spleen meridians) of bilateral lower extremities.
In fibromyalgia, the peripheral sensory thresholds are normal, but pain processing is augmented, primarily due to dysfunction of the descending pain inhibition system in the brainstem.
