Sentence examples for peripheral sensitization from inspiring English sources

One mechanism is the inhibition of neurogenic inflammation by blocking neurotransmitter release from sensitized nociceptors, reducing peripheral sensitization.

It is thought that this heightened pain sensitivity results from both central as well as peripheral sensitization [41, 65].

Central as well as peripheral sensitization mechanisms may play a role in the facilitation.

Consistent with the known pathogenesis of BCP, peripheral sensitization, induced by releasing algogenic substances from cancer/stromal cells, is one important contributor48.

These findings suggest that early life adversity is linked to enhanced central and peripheral sensitization in young adults.

Although previous reports have suggested that P2Y1 receptors (P2Y1Rs) are involved in cutaneous nociceptive signaling, it remains unclear how P2Y1Rs contribute to peripheral sensitization.

Peripheral sensitization of C fibers may be responsible for heat hyperalgesia [19].

This may explain the process of peripheral sensitization developed during the attack of migraine.

TMJ OA patients demonstrated more pronounced hyperalgesia compared with arthralgia patients suggestive of central as well as peripheral sensitization.

In animals, sustained CGRP release may induce peripheral sensitization [105] likely due to release of inflammatory mediators (bradykinin, prostaglandins, etc).

Thus, peripheral sensitization may be of greater importance in the pathophysiology of localized myalgias than in widespread pain.