Sentence examples for peripheral inhibitory effect from inspiring English sources
There were two animal studies 1992 [36] and 1993 [37] which by the authors were interpreted as showing a peripheral inhibitory effect of sumatriptan on primary afferents of the trigeminovascular system but which, as mentioned above, could not exclude an inhibitory effect in the TNC [37].
This brings the developing skeletal elements increasingly closer to the anterior and posterior edges of the limb bud, reflecting attenuation of the peripheral inhibitory effect.
GABAB receptor activation might prevent coughing through peripheral inhibitory effects on bronchopulmonary vagal afferent nerves.
The stimulation of additional peripheral nerve endings has an inhibitory effect on the nerve fibres generating the pain.
The acute antihypertensive effects might be partially due to the reduction of the peripheral arterial resistance by thwarting the acute inhibitory effect of L-NAME on eNOS.
CB1 receptors are predominantly found in the central and peripheral nerve terminals, where they portend an inhibitory effect on γ-aminobutyric acid (GABA).
Moreover, the significant inhibitory effect of drugs was also observed in peripheral organs such as stomachs, intestines, and kidneys– 4(d)).
At the same concentration (5 µM), ODNR01 was significantly stronger than ODNA151 in inhibiting the expression of IFN-γ and IL-17 or Th1 and Th17-cell frequencies, but had no inhibitory effect on IL-4 expression or Th2-cell frequencies in peripheral CD4+ T cells from Th1-biased C57BL/6 mice, while the control ODN1612 had no inhibitory activity (Supporting Information Fig 2A and B).
This observation complements our in vitro data showing that BiP has a significant inhibitory effect on HLA-DR expression and downregulates CD86 expression by human peripheral blood monocytes [ 1] and monocyte-derived dendritic cells [ 10].
On the other hand, it was noted that relatively higher inhibitory effect of recreational drugs was found in renal medulla when compared to other peripheral tissues, suggesting a mechanism by which recreational drugs abuse may cause urinary tract abnormalities.
In contrast, DMF had a significant inhibitory effect on lipopolysaccharide (LPS) induced nitric oxide burst in microglia and induced apoptosis in peripheral blood mononuclear cells (PBMC).
