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Exact(34)
To date, no investigation as to the exact thymic and peripheral expression of a naturally occurring positive selecting self-peptide MHCII (self-pMHCII) complex has taken place.
For Lakoff and Johnson, this non-literal language is not merely peripheral expression useful for adding bells and whistles to the bustle of communication, but reflects something deep about how love is conceptualized.
In prion disease, the peripheral expression of PrPC is necessary for the transfer of infectivity to the central nervous system.
Despite its peripheral expression, a polymorphism located on TPH1 has been reported to influence the response to antidepressant treatment [52].
The peripheral expression of PrPC is essential for transfer of infectivity to the central nervous system [6] and the efficiency of neuroinvasion is influenced by the level of expression of PrPC [7].
In particular, as HIV antigenemia has been shown to affect both bone marrow function and IL-7R peripheral expression [24], [25], we reasoned that HAART-treated lymphopenic patients with full viremia suppression (immunological nonresponders, INRs) might feature a different IL-7/IL-7R profile than individuals with complete immune-virological failure (complete failure, CFs).
Similar(26)
Since the retina-specific α-Cre mice used here do show a central-peripheral expression gradient, so does the apoptosis and, subsequently, retinal thickness.
After haematopoietic stem cell transplantation, patients experiencing graft-versus-host disease had increased peripheral TLR5 expression; adoptive Treg therapy reduced this expression by preventing the disease [ 34].
The peripheral gene expression studies reviewed in this section demonstrate the feasibility of peripherally extracted coding and noncoding RNA to provide insights into brain-based disorders.
To reduce peripheral transgene expression, we explored the safety and efficacy of AAV9/hMECP2 injected into the cisterna magna (ICM).
Further in-vivo investigations with respect to peripheral MCHR1 expression of healthy, obese and diabetic rats need to be performed to further proof the applicability of the MCHR1 concept.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com