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No significant effect of metoprolol on trigeminal pain processing was observed, suggesting a peripheral effect of metoprolol.
The authors' conclusion was that it could be a peripheral effect of the drug because "sumatriptan is a selective 5-HT (1B/1D) receptor agonist that does not cross the blood brain barrier" [60].
These results indicate that an equal dose of CM will not produce an equivalent peripheral effect of cocaine.
The poor differential maps of Ethanol treated animals are unlikely to be explained by a peripheral effect of ethanol to the visual system [9], with Ethanol treated animals presenting visual acuity similar to controls (supplemental material, Results S1, Figure S2).
So in vivo, an activation of the MC3/4-R could affect COUP-TFII gene expression directly through a transcriptional mechanism regardless of the peripheral effect of MTII on the other nuclei.
The miosis that resulted from HA administration is more related to peripheral effect of HA than central effects.
Similar(42)
The proposed remedies, some critics said, treat some peripheral effects of the crisis rather than its thorniest causes.
Noradrenergic pathways are involved in mediating the central and peripheral effects of physiological arousal.
To examine the peripheral effects of BAL on the neutrophil counts and cytokine levels in the circulation.
In this report, the investigators focus on the known cardiovascular, cerebrovascular, and peripheral effects of marijuana inhalation.
Peripheral effects of CGRP are largely confined to its well-known vascular functions, while fast neuronal effects are not established so far in the trigeminal system.
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