Sentence examples for peripheral effect in from inspiring English sources

Some central effects have been mentioned, but the peripheral effect in reducing sympathetic tone and a possible antiinflammatory action may also be involved [ 24– 26].

Considering the potential inflammatory properties, there seems to be a discrepancy between high concentrations of serum S100A8/A9 and the lack of its peripheral effect in patients with RA.

While peripheral effects in adults often go away when lead exposure ceases, evidence suggests that most of lead's effects on a child's central nervous system are irreversible.

Five of eight articles stated this [57].anofi-sponsored researchers claim that hepatocytes contribute to rimonabant's peripheral effects in mice [73].

There is considerable evidence for a peripheral effect of opioids in rats (Obara et al, 2009; Stein et al, #emmm201201980-bib-0046,) and humans (Kalso et al, 2002; Vadivelu et al, 2011), where local application of opioid agonists is antinociceptive under a number of different inflammatory pain conditions.

Taken together, these studies with amlodipine and nifedipine GITS suggest that BP reduction and the effects on the sympathetic nervous system reflect a dynamic equilibrium between central and peripheral effects, which, in turn, are dependent on peripheral (plasma) and central (central nervous system) concentrations of drug.

This finding also suggests the role of a peripheral effect as an early mechanism in hypertension development.

These results suggest that caffeic acid exhibits peripheral analgesic effect in mice and rats and could be further examined for the treatment of chronic painful episodes.

Therefore, one may speculate that the increased cerebrocortical effect of insulin detemir in presence of comparable peripheral effects might be involved in the beneficial effects of insulin detemir on body weight development during insulin treatment.

However, the intensity of these peripheral effects is typically lower in the sham condition than in TMS and only TMS elicits muscle twitches and stimulates facial muscles.

In the current trial, we evaluated the peripheral effects of an HFS diet in adult female rats that had experienced an MS paradigm.