Sentence examples for peripheral depletion from inspiring English sources
This is the first time that the levels of amyloid-β have been measured simultaneously in plasma and CSF and that peripheral depletion has been shown to have no effect on central levels of amyloid-β in non-human primates.
This strategy was successful in avoiding the peripheral Cr depletion and the motor deficits shown by germline CrT knockout mouse.
Thereby, these experiments established experimental cancer cachexia as a state of peripheral energy depletion and loss of body mass, associated with hepatic VLDL hypo-secretion and non-familial hypobetalipoproteinemia.
Indeed, impairment of hepatic VLDL release has been associated with peripheral energy depletion and catabolic wasting conditions, reflecting the importance of VLDL-associated TG and its lipoprotein component ApoB100 as both an energy source and signaling molecules for peripheral organs, respectively (Seelaender et al, 1996).
Therefore, the synergism observed here must be based on mechanisms distinct from peripheral lymphocyte-depletion. Can leukopenia predispose for S. pneumoniae superinfection at all?
As CD20 is expressed on mature B cells but not on plasma cells, it is not surprising that rituximab therapy does not deplete serum immunoglobulin or autoantibodies, even in the context of effective peripheral B cell depletion.
These findings suggest that the higher ocrelizumab dose is more effective in prolonged peripheral B cell depletion.
In the peripheral blood, the depletion of CD4+CD25+ Treg cells did not significantly impact the magnitude of the CD4+ or CD8+ T cell immune response in either HIV-1-EU or HIV-1-infected infants and children.
Peripheral B cell depletion lasts for an average of 6 9 months and sometimes longer [ 3].
Similarly, in Drosophila peripheral neurons, both depletion and ectopic expression of Pum have a detrimental effect on dendrite morphogenesis.
Peripheral B-cell depletion lasted 7 months and 10 months, respectively, and each time was accompanied by a clinical improvement.
