Our data suggest that peripheral mechanical constraints and centrally controlled inhibition may be involved in cuff pressure rise induced deterioration of the swallowing reflex.
It is possible that in the peripheral system the space constraint is less of a limiting factor than in the brain, as axonal myelination in the PNS tends to be optimized for maximizing conduction velocity so that long projection axons can ensure rapid sensory and motor responses [1].
In cardiac imaging, acquisition speed has always been of primary importance; during the past few years several tricks have been used with this aim; in the beginning, speed improvement was achieved thanks to gradient hardware but a further improvement has been limited by physiological constraints such as peripheral nerve stimulation.
This is most likely because of soft-tissue-induced constraints (central vs. peripheral sites) in trabecular bone assessment, as investigated by Bauer et al. [ 43].
However, it differs from studies done on a macroevolutionary timescale, which have consistently reported that accelerated evolutionary rates tend to happen at the periphery of the protein interaction network, likely due to the lower functional constraints for the peripheral proteins (Jeong et al. 2001; Fraser et al. 2002).
These tests allows us to find out that the radial displacement constraint imposed on peripheral wires by the central one in the contact regions constitutes the main source of curve veering.
But countries like Germany have shown little willingness to ease the constraints of austerity for peripheral European countries, or to engage in stimulus spending themselves.
This partitioning was performed because we suspected that tRNAs in the core set are under stronger selective constraints, whereas constraints in peripheral tRNAs are more relaxed.
It's comparable to Microsoft's dilemma with Windows, where moving its huge installed base into the future that's been carved out by OS/10 is gated by the size and downlevel constraints of its target machines and peripherals.
In general, core tRNAs have fewer substitutions than peripheral genes from the same species, suggesting higher selective constraint on these loci.
This network is optimized for multimedia viewing and bypasses congested areas of the Internet by traveling along more peripheral paths so that transmission is smooth despite current narrowband constraints.
