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Although it has been shown that central and peripheral orexin levels increase and decrease in similar proportions, the first limitation of this study may be attributed to the peripheral analysis of orexin levels as a centrally generated metabolite [ 46].
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Outpatients without any hematological or infectious disorders who were recruited at the time of anesthesia evaluation (peripheral blood analysis) or after a BM aspirate analysis considered as normal by hematologist were used as controls for comparison.
Peripheral blood analysis of 3-week-old mice showed mild but significant erythrocyte abnormalities in PiT1neo/neo mice as compared to litter-matched PiT1+/+ mice (Table S4).
Importantly, the in situ expression pattern of the 160 genes derived from the peripheral blood analysis was also predictive of the severity of atherosclerosis in human aorta tissue.
Animals with more than 90% CD45+ GFP+ leukocytes verified by peripheral blood analysis were used for further experiments 6 weeks after transplantation.
Although there was not a transfer of DNA during trogocytosis, our long-term studies and peripheral blood analysis demonstrate that trogocytosis is an ongoing event and was maintained in the recipient mice for 7 months.
Peripheral blood analysis revealed anemia (Hb 6.3 g/dl) and bicytopenia.
However, sequential peripheral blood analysis is more convenient than BM analyses in patients with solid tumors.
Beyond profiling peripheral blood, analysis of tissue-resident T cells provides further insight into immune-related diseases.
PAD was defined based on either the results of peripheral Doppler analysis, or a history of amputation.
This cellular observation in lung tissue did not correlate with a similar increase in peripheral blood analysis.
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