Sentence examples for peripheral administration from inspiring English sources

Overton, J.M. & Fisher, L.A. Differentiated hemodynamic responses to central versus peripheral administration of corticotropin-releasing factor in conscious rats.

(c) Peripheral administration of biperiden (0.5 and 1.0 mg/kg) increased PPI in post-pubertal NVH lesioned rats.

Several technologies have been described where following peripheral administration the molecules can be detected in the brain.

Vasoactive intestinal peptide was the first model chimeric peptide to show an enhanced CNS effect after noninvasive peripheral administration.

Effects of peripheral administration of oxotremorine (OXO; 0.1 and 0.25 mg/kg) and biperiden (0.5 and 1.0 mg/kg) on acoustic startle response (a).

(b) Peripheral administration of oxotremorine (OXO; 0.1 and 0.25 mg/kg) dose-dependently reduced prepulse inhibition (PPI) in control rats as compared with saline injection.

Peripheral administration of CRH antagonists that do not cross the blood brain barrier have been found to reduce spontaneous waking (Chang and Opp, 1999).

In the NK1 research field, gerbils have most frequently been used in a pharmacodynamic assay to assess how well NK1 antagonists penetrate the CNS following peripheral administration.

Neumann ID, Maloumby R, Beiderbeck DI, Lukas M, Landgraf R. Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice.

Peripheral administration of the individual peptide hormones has been shown to reduce food intake (FI) and body weight (BW) in rodent models.

Initial screening of these analogues for CNS activity by monitoring hypothermia induction after peripheral administration defined several compounds (KH11, KH24, KH26, and KH28 KH30) that warranted further investigation.