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However, the periodicity of fire has increased to less than the 30 40 years for which it is probably adapted; this may be driving decreasing population sizes in southern California [58], [66].
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Indeed, we found alteration of the periodicity of rhythmic firing of HGN1 neurons (new Figure 5K and L).
In other words, individual grid cells show both spiking noise and 'noise' due to heterogeneity and imperfect periodicity of the firing rate maps.
Given the spatial periodicity of the firing exhibited by many of the place cells in the current experiment, 2D autocorrelation maps were produced in the same manner as has been used to reveal the structure of medial entorhinal grid cell firing (Hafting et al. 2005).
The model includes many of the features present in the three classes described above, and is able to replicate behaviour from several experiments, including phase precession in response to a phasic medial septum input, theta cycle skipping, and the loss of the spatial periodicity of grid cell firing fields upon a reduction of input from the medial septum.
Thus, there was a high degree of periodicity in the firing patterns of the cells, reflecting the self-similarity of the compartments.
In the simplest version of the model, which we have explored in a series of studies (Kropff and Treves, 2008; Si et al., 2012; Stella et al., 2013), the periodicity of the grid pattern is a result of firing rate adaptation during exploration sessions that span a considerable developmental time.
Great balls of fire!
Establishment of fire breaks following a recent fire.
Place: chamber of fire.
Place: palace of fire.
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