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The changes for each period were randomized for each trial but were kept consistent while the algorithms were run.
All individuals in the two counties who became unemployed during this period were randomized into a treatment group or a control group based on their birthday.
Methods: Video clips of posterior pole images captured at the examination closest to 33 weeks' postconceptional age of 32 infants screened during an 18-month period were randomized.
Patients with a level of HbA1c≥8.0% at the end of the run-in period were randomized to continue ongoing insulin therapy plus either metformin or placebo tablets for 12 months.
The participants who met the inclusion criteria after the baseline period were randomized into one of three groups: relaxation, exercise, or topiramate.
Patients who met the core study eligibility criteria during the 3-week screening period were randomized (4:1; blocked by center) to receive CAD106 (150 μg) or placebo.
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In practice, a fixed recruitment period of 18 months is considered and all patients recruited in that period be randomized unless sample size after 18 months is below 1002 patients, which would lead to an extension of the recruitment period.
A total of 8436 patients tolerating both periods were randomized 1 1 to either enalapril 10 mg b.i.d. or LCZ696 200 mg b.i.d.
Of the 119 patients who entered the baseline period, 93 proceeded to the 12-week treatment period and were randomized to receive BOS (n = 51) or placebo (n = 42).
During the experimental period, headaches were randomized to one of three stimulation doses, including full-, sub-perception and placebo stimulation.
After recording 1 episode of AF in the screening period, they were randomized to receive azimilide 125 mg or placebo once daily.
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CEO of Professional Science Editing for Scientists @ prosciediting.com