The conclusion stage is a period of normalization of organization, discharge of resources, and little clinical activity.
Followed by an inevitable over-sexualization, sideshow-esque curiosity, or hopeful period of normalization.
After the invasion, Czechoslovakia entered a period of normalization: subsequent leaders attempted to restore the political and economic values that had prevailed before Dubček gained control of the KSČ.
We experienced precisely such an event in the early aughts, the Al Aqsa intifada, which disrupted a long period of hopeful normalization and kicked off a decade of tension and periodic war.
Cancer treatment with anti-angiogenic drugs induces a short period of vascular normalization with improved tumor oxygenation, followed by impaired tumor perfusion leading to increased hypoxia and lack of nutrients [ 20, 21].
After the Soviet Union invaded Prague, ousted Dubcek, and instituted a period of hard-line "normalization" that lasted for more than twenty years, the Communist Party banned Havel's works.
Both groups will be treated with the same sequential approach during the 8-hour study period pursuing normalization of capillary refill time versus normalization or a decrease of more than 20% of lactate every 2 h.
In the immediate neonatal period, the physiologic ductal closure associated to hemodynamic changes usual to this period allows normalization of the cardio-circulatory alterations secondary to the increased right ventricular overload.
These include the need for better dosing strategies; the frailty of cancer patients who are much sicker than tumor-bearing mice and therefore cannot withstand the toxicities associated with high dose therapy; and "vascular normalization", a period of time following anti-VEGF/VEGFR therapy in which tumor vessels normalize structurally and lose their hyperpermeability.
Since the number of total nodes with degree k is a constant (p k N) during the period of epidemic spreading, the following normalization conditions hold: S_{k}(t)+I_{k}(t)+R_{k}(t)=1,quad k=m,m+1,ldots,n.
This could also explain our results showing that OPG and RANKL levels were significantly lower at 2 years in Charcot patients than in diabetic controls, as Charcot patients have had a long period of immobilization without weight bearing, allowing normalization of RANKL and OPG levels, although we can only speculate about the duration of these changes.
