Indeed, cellular assays, while perhaps noisier and more challenging to deconvolute results, better inform the medicinal chemist with respect to the inhibitor effects in the presence of physiological concentrations of ATP (biochemical assays are most often performed at lower ATP concentrations, which makes the inhibitors appear more potent than they would be in the cellular environment).
On Friday night the defending champion reached the third round with a 7-5 6-1 3-6 6-1 victoverover Argentina's Leonardo Mayer in Louis Armstrong Stadium, which is perhaps the noisiest of all the courts here.
But the marketing onslaught is notably less noisy, perhaps reflecting the diverting of promotional dollars online or a recognition that bigger outdoor ads aren't always better.
I suggested that if she found it too noisy, perhaps a café rather than a mall food court might better suit.
Table games (that are not usually noisy), perhaps even games in the computer are the solution.
Perhaps so, although a noisy generator, a low-flying helicopter, power-hammering from a nearby building site and the chatter of the press made Zumthor's exquisite hidden garden feel more like opening day at the Chelsea flower show than a retreat into floriated, birdsong-haunted monastic calm.
It was terrific to see players like Haggerty, Karl Fitzpatrick and Stuart Littler raising their games and putting their bodies fearlessly on the line, perhaps inspired by the noisy support they received from the Blarney Army - with their splendid aim of making the young prop from Carlow "the most famous Wayne Kerr in the world".
So unaccustomed to quiet are they that they reach for their Smart phones (perhaps to play a noisy video game), or they turn on the TV, or they chatter away even when they have nothing to say.
Perhaps hypochondriacs just have noisier bodies or a greater sensitivity to everyday bodily sensations or both.
The Beeb's solution has been the introduction of sound-deadening curtains and carpet, (perhaps those who live in noisy flats should take note) which they believe has solved the problem.
