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More modest recovery in the ventilation perfusion ratio may still continue to improve oxygenation at higher PEEP levels.
Normally patients with pulmonary disorders will have some abnormalities in the ventilation perfusion ratio because of an impaired gas exchange mechanism [27].
This could be due to the presence of some abnormality of the ventilation perfusion ratio because of the primary pulmonary pathology resulting in hypercapnia.
The perfusion ratio per time point was calculated by dividing the perfusion of the ligated (ischemic) by the non-ligated (non-ischemic) hind limb.
Semi-quantitative analysis of 3D perfusion data sets in eight healthy volunteers allowed for calculation of the left-to-right perfusion ratio (ratio 0.9), which was confirmed by phase-contrast flow measurements [68].
This causes diversion and overperfusion of the pulmonary blood flow to the unaffected areas within the lung, away from the embolised area leading to a low ventilation/ perfusion ratio causing hypoxaemia [40].
Similar(30)
Recruitment of collapsed alveoli by positive end expiratory pressure (PEEP) titration and optimization of ventilation-perfusion ratio by prone positioning have been extensively described in animal and clinical trials.
They may include effect of low mixed venous oxygen tension (PvO2) on arterial oxygen tension [1], intra-cardiac right-to-left shunt [2], low ventilation-perfusion ratio [3], or intrapulmonary shunt [3].
Hypoxic pulmonary vasoconstriction may be responsible for maintaining the ventilation-perfusion ratio during localized alveolar hypoxia.
A first metric was defined intuitively as the volume integral of the TRP-to-perfusion ratio (HPR).
Moreover, quantitative CT reflects the average density of pneumonia and surrounding lung parenchyma, which may vary depending on preexisting regional ventilation-to-perfusion ratio.
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