The 3D alveolar capillary model permits investigation of the impact of alveolar geometrical parameters and diffusion and perfusion coefficients on the in vivo measured 129Xe CSSR signal response.
Images will be retrospectively analysed to determine the apparent diffusion coefficient and tumour perfusion coefficients (Ktrans and Kep) at each time point.
Thus, our purpose was to test the within-subject (test retest) repeatability of the perfusion fraction, diffusion coefficient, and pseudo-diffusion coefficient in various foetal organs and in the placenta.
Our purpose was to test the within-subject (test retest) reproducibility of the perfusion fraction, diffusion coefficient, and pseudo-diffusion coefficient measurements in various foetus organs and in the placenta based on the intra-voxel incoherent motion (IVIM) principle.
Thirty-six unique alpha and b-value sample points from 5 different gradient waveforms were used to reconstruct perfusion fraction (f), coefficient of diffusion (D), and blood velocity standard deviation (Vb ) maps using a recently proposed IVIM model.
Perfusion fraction (f), diffusion coefficient (d), and pseudo-diffusion coefficient (D*) were calculated.
For regions associated with the DMN we observe similar patterns of covariation, but complemented by a positive covariation of degree and betweenness and a negative covariation of the clustering coefficient with perfusion, in a range of minor to medium magnitude.
On a regionwise level, frontal, cingular and hippocampal regions show a negative covariation of perfusion with the clustering coefficient and local efficiency, while mainly posterior portions of the brain show a positive covariation particularly with vulnerability.
For example, studies have shown that using IVIM analysis, cirrhotic liver shows a lower perfusion fraction and pseudodiffusion coefficient.
Apparent diffusion coefficient with perfusion-influenced b-values.
