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MSCs are present at a low frequency in the BM; therefore expansion is necessary before performing clinical studies.
Given the vulnerability of some subpopulations and the challenges and costs of performing clinical studies in these populations, cutting-edge approaches are needed to effectively develop evidence-based and individualized drug dosing regimens.
With increasing millennial interest in these nontraditional remedies, researchers are taking notice and performing clinical studies that show them as being ineffective.
This work has some limitations derived mainly from the lack of experience of the local ophthalmologists in performing clinical studies and collecting data in an appropriate form, but it can be considered as the first attempt to develop ophthalmic clinical research in Angola.
A final recommendation applies to those individuals who have the capabilities of performing clinical studies concerning stress ulcer prophylaxis.
A major purpose of this study area is to predict pharmacokinetic properties of new drugs in humans, without performing clinical studies, in order to accelerate the efficiencies of new drug development processes.
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W.R.B., G.M.P., N.M. and L.T.A. designed and performed clinical studies, obtained samples and performed human data analysis.
First, we critically review the technical solutions proposed in the literature to perform clinical studies.
In order to validate new biomarkers and perform clinical studies high quality biobank samples are of key importance.
ADPC and AL performed clinical studies.
JKD performed clinical studies with and received honoraria from Novartis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com