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While most studies are performed with the endpoint of cancer, the intermediate phenotype has been overlooked.
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Therefore, the study was performed with the endpoint pLOS.
A meta-analysis of these data was performed with the primary endpoint of mortality within three months after pulmonary embolism, and a secondary endpoint of overall mortality and morbidity by pulmonary embolism.
Power calculations were performed with the primary endpoint TNFα and the secondary endpoint VO2 since we wanted to investigate whether the known anti-inflammatory and metabolic lowering effects of ALM would translate into an improvement in organ function.
At three-months post-ICU, the PDS [ 17] was performed as the endpoint of the study.
Kaplan-Meier survival analysis was performed with the type of cup as the independent factor and revision for any reason as the endpoint.
Kaplan-Meier survival analyses were performed with the type of fixation as the independent factor, and revision of any component and for any reason as primary endpoints.
The primary and secondary efficacy endpoint analysis will be performed with the intent-to-treat population.
The analysis of the treatment effects with respect to the secondary endpoints PFS and OS will be performed with the Cox model.
Kaplan-Meier survival analysis was performed with two endpoints: (1) revision procedures of the acetabular component and of the stem for aseptic loosening, and (2) revision procedures of the acetabular component and the stem for any cause.
Only one recent randomized controlled study suggested a decrease in 90-day mortality (secondary endpoint) associated with fluid vascular loading performed with colloids, the absence of deleterious effects in terms of 28-day outcomes (primary endpoint) and the absence of a higher risk of AKI (secondary endpoint) [15].
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