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From Figure 3 and several other simulations that we have performed, we find that this theoretical curve provides a better fit to the simulated genetic diversity when b/e is small, with deviations appearing when both this ratio and R0 are large (compare panel A in which b/e = 0.05 and panel B for which b/e = 0.15).

While quantification of H2O permeance was performed, we found it was affected by concentration polarization even with small membrane area and a low stage cut.

When multi-diet cross-gender comparisons of co-regulated genes were performed, we found that this specific gene-set was entirely CR-specific (Figure 8).

When this was performed, we found tumor growth at both bone marrow and subcutis with ex vivo cultured myeloma cells.

After careful optimizations were performed, we found that although Cu OAc 2 and PivOH did promote this catalytic process, the use of co-oxidants of BPO (2.0 equiv).

In the simple sensitivity analysis performed, we found a more pronounced effect of increased mortality than increases in various ICU costs.

Although extensive analysis was performed, we found no association between CXCR1 and CXCR2 expression and patient outcome in the overall cohort (stage II and stage III tumours).

In both case control studies performed, we found a significant difference in global leukocyte DNA methylation between individuals with cancer and unaffected controls (p < 0.001; Table  1).

When latent class proportional hazards analysis were performed, we found two distinct latent classes within our cohort, reflecting different susceptibilities of dying from BC based on their baseline characteristics.

Spearman analyses were not part of our original protocol, but when performed we found constant negative correlations ranging from –0.040 to –0.378 (statistically significant at 8 weeks and 2 years) at all follow up times (data not shown).

When a BLAST (http://blast.ncbi.nlm.nih.gov/Blast.cgi) search in GenBank was performed, we found that some genotype 4 isolates obtained in this study shared the highest sequence homology with previous swine strains.