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The identification of suitable epigenetic CCA biomarkers with high sensitivity and specificity may facilitate cancer diagnostics at an early stage, perhaps performed upon biliary brush specimens, and thus contribute to increase survival of this patient cohort which presently carries such a poor prognosis.
Brushing of a specimen shall be performed with the specimen mounted in a specimen holder.
Recruitment was performed upon hospital admission.
Further passages were performed upon confluence.
All specimens had an aPTT and a chromogenic anti-FXa assay performed on each specimen regardless of heparin type.
In this study, experimental investigation was performed for each specimen.
The loading experiment was performed with a specimen of ultramylonite.
The specimen is iridectomized and cataract extraction performed; the specimen is then placed in culture.
Splitting tests were performed on the specimens at −30 °C.
Tensile testing was performed on 20 specimens for each treatment.
‡Retrospectively performed with cryopreserved specimens.
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