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Extensive simulations were performed to compare the performance of the proposed algorithm with existing algorithms.

Chi-square tests were performed to compare characteristics between groups.

Kruskal Wallis tests were performed to compare expression levels across breast cancer subtypes.

(A) CETSA was performed to compare crizotinib ALK binding ability between RU and RR cells.

The unpaired two-tailed t-test was performed to compare groups.

Two-tailed student's t-test was performed to compare two groups.

Student-Newman-Keuls was performed to compare effects on new cartilage formation among groups.

Factorial-design ANOVAs with post hoc Tukey's tests were performed to compare data from independent samples.

Statistical tests were performed to compare the expression between different tissues and groups of tissues for each aquaporin group.

MS/MS and coelution analysis were performed to compare the synthetic peptide with its in vivo counterpart (Fig. 2a, b).

A Student's t-test was performed to compare means between experimental and control groups at a single time point.

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