Results in Figure 3 suggest that in situations where this assumption is not satisfied, we can expect reduced prediction performance if we naively apply Gaussian-based methods, (GLASSO) or if we perform insufficient data preprocessing (Log-GLASSO).
The Network also suggests using the term inactive in describing "those who are performing insufficient amount of moderate- to vigorous-intensity physical activity (MVPA) (i.e., not meeting specific physical activity guidelines)" [ 10].
It is unclear how many measurements are needed for sufficient accuracy and reproducibility, but it seems that three, although clinically mostly performed, is insufficient.
Furthermore, whole genome amplification may be performed when insufficient DNA is available from a sample [ 7- 9].
*Not done, not performed if insufficient brain material was available for cerebral inoculation or if the infected brain failed to propagate in the cell line.
However, as mentioned above these studies were performed with insufficient radiation dose and whether the benefit from the prolonged HT was from a local or distant effect, or a combination of both is unknown.
Hormone receptor status was not known for 16.3% of the patients, either because patients refused a histological biopsy, or because only a fine-needle biopsy was performed or insufficient material was obtained by large-core needle biopsy.
The lack of confirmation of some of the associations is usually ascribed to differences in some aspect of the genetics of the trait or aspects of the sample, and lack of confirmation is most generally ascribed to false discovery due to the large number of tests performed or insufficient power in the original GWAS [ 3, 4].
Additional comparisons between specimens was hampered by the exclusion of sample results due to insufficient sample quality to perform sequencing, insufficient sample to perform the genotyping analysis or genotyping results indicating that the samples were not from the same individual.
Analysis of different CT studies was not performed due to insufficient numbers for meaningful results in each separate category of CT scans.
