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If only P SPECT was performed calculated breast absorbed dose was 0.25mGy [ 10– 10].

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Buccal bone measurements (in mm) were performed calculating the distance to the buccal bone outline minus the radius of the interior contour of the implant.

Correlation analysis was performed calculating Pearson's coefficient.

A non-linear regression was performed calculating the gestational age (age) as a function of CRL.

Correlation analysis was performed calculating Pearson's correlation coefficient.

Bivariate correlations were performed calculating the Spearman rho coefficient.

Correlation analysis was performed calculating Pearson correlation coefficients.

Correlation analysis was performed calculating Spearman-Rho (r).

Trend analysis was performed, calculating differences between consecutive measurements.

Univariate analysis was performed, calculating relative risks (RR) and 95% confidence intervals (CI) for dichotomous individual exposures.

Growth curves and expansion ratios were performed and calculated as described in the Extended Experimental Procedures.

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