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We validated the performance of this assay for evaluating specific genetic alterations in both normal and cancer reference standard DNA samples.
We describe a large, prospective, multicenter study done to verify the performance of this assay.
The aim of this study was to evaluate the analytical performance of this assay.
Performance of this assay was evaluated in combination with two different internal amplification controls (IAC), a competitive one specific for the assay and a universal IAC based on plasmid pUC19.
The performance of this assay for detecting FLU and RSV viruses was compared to the traditional methods (culture and/or direct florescent antibody testing) using 945 nasopharyngeal swab specimens.
Since performance of this assay does not appear to be influenced by differences in HIV-1 subtypes A, C and D, it has the potential for use in the detection of HIV-1 DNA in samples from geographic areas where these subtypes are prevalent.
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We comprehensively evaluated both the analytical and clinical performances of this assay.
Performance characteristics of this assay are described in another publication under preparation (De La Barrera R and others, unpublished data).
The analytical performance of this new assay was evaluated.
Approaches to improve upon the analytical performance of this simple assay are highlighted.
The performance of this new assay for quantitation of HCV viremia was evaluated with 213 anti-HCV positive sera, 120 of which corresponded to 30 patients sampled during the therapy.
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