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As an initial step for evaluation of performance of the hydrogels in the biological environment, the in vitro biocompatibility of these hydrogels, was evaluated using L929 mouse fibroblasts.
Acrylamide (AAm) was used to increase the lower critical solution temperature (LCST), while sodium alginate (SA) was used to improve the swelling performance of the hydrogels.
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However, the interface that forms between each layer has the potential to affect the performance of the hydrogel.
Also the morphology and the quantity of PEDOT formed in the hydrogel were considered to be the key factors for improving the mechanical performance of the hydrogel.
In addition, the mechanical performances of the hydrogels were measured by a universal testing machine.
Herein, the chemical structure, as well as microscopic morphologies, mechanical and self-healing performances of the hydrogels were investigated.
The biological performances of the hydrogels were evaluated by cultivating porcine iliac endothelial cells (PIECs) in vitro.
Both the physical and biological performances of the hydrogels could enhance cell viability and proliferation, particularly in Gel Ch CCP (1 1 0.1).
These unique performances of the hydrogels make them promising candidates for in vivo evaluation in clinical studies aiming at tissue regeneration.
The concentration of oxidized constituents (i.e., oxidized alginate and hyaluronic acid) and gelatin in composite was varied and physical, mechanical and functional performances of the hydrogel were screened.
In the aqueous sample of a fixed volume, the total mass of the INA particles (m) was found to be the governing parameter that is solely responsible for determining the ice nucleation performance of the bacterial hydrogel beads.
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CEO of Professional Science Editing for Scientists @ prosciediting.com