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One series of 41 patients has been reported by Zemskova et al. but several imaging modalities were used, not in all patients, with intervals of several months, PET being performed as a second-line examination when others were not conclusive; so, performance of modalities cannot be compared [ 141].
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There are several studies comparing the diagnostic performance of these modalities, with breast MRI reported to be the most accurate imaging modality for assessment of tumor extent and LN status [ 4- 7].
However, test performance of screening modalities was not subject to sensitivity analysis in some studies [27, 77].
The improved test performance of newer modalities was captured, but their downstream effects for screening/follow-up were dated.
Prior studies have focused on the diagnostic performance of noninvasive modalities using angiographically significant stenoses as the reference standard.
In diagnostic medical imaging the performance of imaging modalities needs to be tested and evaluated on a regular basis in order to ensure correct functionality and optimal image quality.
Therefore, we would expect the performance of individual modalities to vary depending on the scenario, and the robustness of the multi modal constraint could be further enhanced by a contextual weighting.
We believe that nanotechnology has the potential to improve the performance of imaging modalities.
In addition, technological advances may further improve the performance of new modalities such as PET.
This could be the first meta-analysis in assessing the performance of imaging modalities in the evaluation of the resectability/unresectability of HCC.
The links between the performance of imaging modalities and the judgement on the resectability of HCC have not been systematically reviewed.
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