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We next examined the performance of each mouse, to assess which individual mice learned the task, and if so, at what trial number in the training session.
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Data are shown as fold increase of motor capacity measured at different time points (21, 28 and 35 days post transplantation) and were normalized with the baseline performance (pre-transplant) of each mouse.
The motor coordination and performance of each new cohort of the mouse was evaluated 30 min after oral treatment of MEPH in a rota-rod apparatus.
Thus, it is conceivable that motivational factors differentially affect cognitive performance of different mouse strains.
From Table 1, we find that the performance of WT mouse is obviously lower than OB mouse.
In each trial, we released a mouse into the pool from a determined position along the wall, and the performance of the mouse was monitored by a CCD camera/image analyzer.
The more in detail analysis of the performance of the mice, was performed using a custom-designed analysis program the jTracks software [17].
In line with better test performance of PrP+/+ mice, PrP+/+ mice showed significantly reduced post-ischemic brain injury when compared with WT mice and PrP−/− mice.
To test for probable correlations between the measured molecular elements and the modified cognitive performance of stressed mice, we plotted the route traversed by each mouse in the first quadrant as a function of the levels of relevant RNA transcripts.
Figure 1 summarizes the performance of the three mouse strains in the initial set of olfactory tasks.
The performance of mouse apoE in binding to lipid emulsions, solubilizing DMPC MLV, and interacting with VLDL particles is closer to that of apoE4 than to that of apoE3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com