Both dietary treatments led to significantly better performances of total alternation in the continuous spontaneous alternation task than that displayed by the CTL group without changes in partial alternation.
Main effects of treatments were observed in the continuous spontaneous alternation task, in which both CR and RSV supplemented animals presented better performances of total alternation compared to CTL animals.
However, the L-745,870 doses of the present study were chosen, because the D4 antagonist is highly selective in these doses, and significant effects on performance of a learned alternation task have been found previously using comparable doses of L-745,870 (Zhang et al., 2004).
Increasing the length of the delay between the sample run and the choice run reduced the levels of alternation performance in both sham and OFC rats, but did so to an equal extent in both groups (Fig. 6B).
In contrast, CPEE offspring did not have impaired performance of the rewarded-alternation Y-maze task.
This study was designed to examine the effects of early postnatal injection of PCP on later acquisition and performance of a delayed spatial alternation task, a procedure that is sensitive to manipulations of the prefrontal cortex.
Performance of the spatial delayed alternation task in a T maze is very relevant to many aspects of ADHD.
Efficient performance of the task required alternation of choices between persistent and sporadic objects, with the switch occurring when reward had been earned for selection of one category.
Data were analyzed using analysis of variance (ANOVA. Planned comparisons were performed with a test of effects using Systat software. The effects of restraint stress on performance of the spatial delayed alternation task were examined in males (n = 7), and in cycling females in either estrus (n = 5) or proestrus (n = 5).
For example, some research show that lower dose of MPH could improve the performance in delayed alternation task, sustained attention task [ 20, 21] and spatial learning and memory task [ 22] in rats of ADHD models.
To quantify performance of the W-track continuous alternation task, we parsed the running behavior into trials and classified the trials as inbound or outbound according to their point of origin on the W track.
