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We will perform intention to treat analysis.
Access to data at the level of the patient enabled us to uncover previously unreported data, improve the assessment of study quality, perform rigorous quality checks, standardise outcome measures, and perform intention to treat analysis.
Another review concluded that there was moderate quality evidence that exercises and mobilisations commonly used by physiotherapists were effective[ 13], but this was based on just three small trials, which reported short-term outcomes only, did not perform intention to treat analyses, and did not have blinding of outcome assessment.
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Of them, three did not perform intention-to-treat analyses [ 19, 20, 23].
Third, although details of dropouts and withdrawals were described in four RCTs, three studies did not perform intention-to-treat analysis, which might have lead to attrition bias.
Missing data compromise the ability to perform intention-to-treat analyses in randomised trials [ 17], and because the risk factor profiles of non-responders may differ from those of responders, the effect of risk factors is not easily predicted [ 18].
We will perform intention-to-treat analyses using repeated measures analyses (Mixed Models) to measure the effectiveness of the web-based treatment program in terms of primary and secondary outcomes.
Two studies did not perform intention-to-treat analysis, having lost one and two participants to follow-up respectively [ 43, 48]; in each of the other five studies [ 30, 44- 47], the use of "last observation carried forward" was necessary to impute continuous data missing at follow-up.
9 10 Four studies performed intention to treat analysis.
In all, 13 (65%) trials performed intention to treat (ITT) analyses (see Supplementary material).
However, only 2 out of 4 studies performed intention to treat analysis [ 30, 40].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com