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For quite some time we have been developing a multivariate modeling approach, termed proteochemometrics (PCM), that can perform concomitant analysis of the interactions of multiple proteins with multiple ligands.
This is further proved by data in Additional file 1: Figure S1, where we perform concomitant analysis of a chromatin density region marked with Hoechst 33342 (A) and H2B-EGFP (B).
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We did not perform an analysis on concomitant diseases and we did not have any data on dementia and Parkinson's disease, which could represent a limitation.
We then perform correlation analysis.
Clearly, we can perform such an analysis.
RJ performed SIMS analysis.
IZ performed metabolomics analysis.
ZZ performed data analysis.
To check whether changes in mRNA level result in concomitant disturbances of protein expression we performed Western blot analysis of two splicing factors, SF2/ASF and hnRNP A1 on twelve representative pairs of control and tumor samples (Fig. 4).
Furthermore, the number of tests performed with concomitant inflation in type I error also plagues the statistical analysis of microarray data, since the number of tested quantities in a study significantly affects the family-wise error rate.
We performed gene expression analysis to identify molecular predictors of resistance to preoperative concomitant trastuzumab and paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide (T/FEC).
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