Your English writing platform
Discover LudwigSimilar(60)
To understand the properties of this molecule and the effect of the mutations on cofactor activity, we used the same preparation of recombinant protein to perform three different experiments.
Potential mechanisms which CMV could use as a cofactor have been described in vitro and potential criteria for assessing cofactor activity in vivo have been proposed.
These findings are consistent with the cofactor activity of sCR1 for factor I-mediated degradation of deposited C3b/iC3b to C3d.
CFH retained cofactor activity when bound to B. burgdorferi s.s.s
Next we determined whether CFH also retains its cofactor activity after previous binding to B. recurrentis.
Peptide IWDYA inhibited cofactor activity, although not completely [Figure 3A ].
This identified multiple pyrrolidinones which inhibit its polymerase cofactor activity.
Using overlapping peptides, we identified amino acids D and Y as contributors to cofactor activity.
Even at 500 µM peptide there was still approximately 25% cofactor activity remaining (not shown).
Control experiments demonstrated that further incubation with thrombin does not result in increased cofactor activity.
Cleavage at Arg has been shown to be essential for full loss of cofactor activity [ 32].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com