Exact(1)
In general, each expert should perform causality assessment independently, and each expert should be blinded to treatment assignment where feasible.
Similar(59)
The experts should, where possible, be blinded to treatment assignment and should perform the causality assessments independently prior to seeking consensus.
We performed causality tests to identify the presence and direction of causality among the model's variables, particularly mobile money balances and private sector credit.
Owing to data constraints, it was unfeasible to perform a formal causality assessment for the cases, although reported ADEs were examined to exclude obvious deviations from our aim (eg, drug dependence reported for hypertension treatments).
Ideally, during drug development, causality assessment should be performed prior to unblinding the treatment assignment within the company.
However, it was not clear whether the authors performed any formal adverse drug reaction causality assessment, even though they stated that the reaction was "probable".
AEs will be scored as grade 1 (a mild AE) to grade 5 (death related to the AE), and a causality assessment will be performed.
3.1 ), and in the absence of hepatology experts, causality assessment should be performed by two or three physicians who are trained and experienced in the process of causality assessment and are blinded to each other's assessment and to treatment assignment.
Analyses were performed in three reported cases (3, 4 and 5) to assess contribution to causality assessment; significant findings, or lack thereof, are described in table 4. Implementing active surveillance into community pharmacies markedly improves the detection of AEs reported by patients taking NHPs.
A causality assessment to PPI was performed using the Naranjo probability scale.
The causality assessment for AEs will be performed according to the WHO-UMC standard [ 25].
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