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The sctt mutant provided a unique opportunity to perform a structure-function analysis at single amino acid resolution of this evolutionarily conserved motif within an intact developing organism.
To make map TBP-specificity the authors should perform a structure-function study on HUWE1.
We subjected these polypeptides to nucleosome remodeling and ATPase assays to characterize the CHD7 basic properties, perform a structure-function analysis of CHD7 and examine point mutants reported in human patients.
DOI: http://dx.doi.org/10.7554/eLife.07777.005 In an effort to perform a structure-activity relationship analysis, we resynthesized compound 1 in-house and were surprised to find that the resynthesized compound was completely inactive in the transcription assay.
The PCP will perform a structured physical examination to assess red flag symptoms in children with clinical symptoms at 12 months.
The aim of this study was to perform a structured literature search and identify the most appropriate paper and pencil tests for INPH.
For this purpose, we perform a structured literature review: we examine existing ATM frameworks, review determinants of ATM and define at which level of the health system they are likely to occur; we analyse to which extent existing ATM frameworks take into account access constraints at different levels of the health system.
It is possible to perform a structural alignment on structures produced by structure prediction methods.
In order to determine whether RbTlCl3 shows CDW or not, we performed a structure optimization study by minimizing the total energy.
We performed a structure activity relationship (SAR) study of 1,2,4-bis-aryloxadiazole to determine which moieties of the molecule are critical for AHR activation.
We performed a structure analysis with two sets of SNPs in bitter taste receptor genes: (1) including only nsSNP and (2) a set composed of SNPs from noncoding and coding region.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com