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(2005) used a complex procedure based on hierarchical likelihood to perform a robust analysis.
Only 6 cases expressed a combined CD44+/CD24−/low/ALDH1+ phenotype and while this number of tumors is too few to perform a robust analysis we did observe that 2 (33%) were basal-like tumors and the remaining 4 (67%) were luminal tumors.
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Here we readdress this issue in human term placenta by performing a robust analysis of allele-specific expression of 22 X-linked genes, including XIST, using 27 SNPs in transcribed regions.
AMIGO_RIdent performs a robust analysis using a Monte Carlo-based approach to generate the robust confidence hyperellipsoid and to provide relevant information regarding correlation of the parameters and robust confidence intervals.
Areas where studies seemed to perform poorly were: performing a robust analysis of uncertainty (Q5, four studies), inclusion of all major short-term and long-term maternal and fetal outcomes (Q10, no studies), and incorporation of a time horizon that included the effects within-pregnancy and lifetime for the mother and infant (Q8, one study).
We used a systematic approach to evaluate the quality and risk of bias in each study, which allowed us to perform a robust sensitivity analysis between quality groups.
To perform a robust Rasch analysis on each of these domains, we included all their candidate items, even though some did not meet the variance criterion.
Because the studies evaluated test-retest reliability using different statistics, we could not perform a robust meta-analysis.
For this reason it becomes practically impossible to perform a robust and comprehensive analysis that requires multiple simulations such as sensitivity analysis, uncertainty quantification and optimization.
Secondly, by adopting a difference equation math approach and design of experiment we perform a robust what-if analysis of a CLSC under a variety of operational and market conditions.
Models were obtained though evolutionary optimisation, which is a stochastic process, so multiple runs were performed for a robust analysis of results.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com