Exact(8)
A simple counterexample makes the point: create a fake Study 3 which is Study 2 with the values of the condition and control swapped; then by the above definitions, all genes are perfectly coherent for studies 2 and 3, having coherence (reproducibility) scores equal to 1; yet each gene which is up-regulated in study 2 is down-regulated by the same amount in study 3, so all genes are inconsistent.
That's fine, that's their perspective, there's a perfectly coherent, intellectual argument to support that.
The most effective counterfeit realities are those which provide what only conspirators seem to have: a perfectly coherent plot.
These are perfectly coherent ethical positions: they don't happen to be positions that I subscribe to, but if that is what Ridley thinks, so be it.
Many philosophers think that it is perfectly coherent to imagine that all of the people one encounters are actually "zombies" who behave and perhaps even think in the manner of a computer but do not have any conscious mental states.
More annoyingly for authors, articles that were perfectly coherent were sometimes turned with a few tweaks, deft as a paw-dab from one of his beloved cats, into pieces that said something quite different from what had been intended.
It is not just that he seems to have read and formed a perfectly coherent opinion about everything, or that he enjoys an easy rapport with a pompous and severe literature professor (Jacques Bonnaffé).
The reason for hearing the set, though, is Harnoncourt's miraculously organic account of those three movements that were composed, every detail perfectly coherent and delivered luminously by the Vienna Philharmonic.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com