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It has been suggested that the percentage of responding patients is lower in everyday clinical practice than that observed in RCTs, possibly because of patient selection, the use of a washout period before inclusion (which may artificially increase disease activity), and differences in doses, co-morbidities and adherence to therapy.
In the ART group, the mean percentage of responding cells was 1.1%, fewer than 20% of which were polyfunctional.
In this set of experiments, anti-CD3-coated beads were used to stimulate the naïve CD4 T cells in the co-cultures with autologous DC, to obtain a higher percentage of responding CD4 T cells and amplify the phenomenon.
For the purposes of quantification, the functional capacity of EBs has been defined as the product of the percentage of responding EBs and the average change in [Ca2+]i under a specific condition.
The highest percentage of responding patients was observed in the intermediate dose group, where 75% of the evaluable patients responded.
The table shows valid numbers and percentage of responding trainees (in brackets); means ± standard deviations (SD) of hours.
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Responses to HIVgag peptide stimulation (i.e., percentages of responding CD8+ T-cells) were first analyzed individually, as summarized in Figure 3.
The high percentage of movement-responding neurons is in line with other studies that have found an increase in the probability of response to movement in the parkinsonian state compared to the normal state [10], [15], [16], [26], [27], though the percentages of responding neurons obtained in our study are even higher.
We conducted a descriptive analysis of the survey, presenting data as percentages of responding ICPEG.
Frequencies of IFNγ+ cells and percentages of responding mice were comparable between TG1050 immunised HBV-free (PBS) and AAV-HBV mice.
38, 48, 55, 57 Remarkably, these studies included fewer patients and showed lower percentages of responding patients compared with the other 6 studies.
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