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The expected percentage of insertion into the repeat if Tn7 inserts at random was calculated to be about 9%.
Number in each bracket is the percentage of insertion sites.
The percentage of insertion and substitution reads were similar between CLIP and input samples and cannot be used as CIMS signatures [ 31].
Additionally, utilizing the report of characteristic frequency of auditory neurons instead of percentage of insertion depth allowed the use of a semi-logarithmic scale, which is more relevant for clinical application than relative depth of insertion.
Mutant mice completed a higher percentage of insertion, reversal and omission types of syntactic chains than wild-type mice (F 4, 184) = 129.01, p < 0.001; each subtype; Figures 2 & 3).
Similar(55)
Comparing the data obtained in vitro before infusion and in vivo, we found that the percentage of insertions inside genes was reduced after in vivo engraftment.
In vivo T-cells and granulocytes from HSC-GT displayed a slightly higher percentage of insertions surrounding the TSS compared to the in vitro dataset, while there is no indication of in vivo skewing in the PBL-GT samples.
Consistent with previous reports, the T2/GT2/tTA transposons exhibit local hopping, where a significant percentage of new insertions cluster in a particular region of the genome, and the insertions can land in genes [ 4, 5].
Even the small percentage of NCCC insertions (3.0%) may be explained by complex events with underlying CCC disrupted by SNPs.
Compared with the shared insertions, a much smaller percentage of the unshared insertions are predicted homozygous loci (A123-1, 25%; A123-2, 10%), whereas a much larger percentage are predicted heterozygous (A123-1 62%; A123-2, 82%).
In this test, we found that a negligible percentage of novel TE insertions (<1%) had de novo piRNA signature in any of the other strains.
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