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Comparable percentage of discrepancy (2.7%, n = 114) was observed between the CKD-EPI Cys and the CKD-EPI mix but with these equations, the differences between positive and negative screening were not uniform.
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Since the main aim was to assess the change in relative risk by response wave, and because we needed a non-differential measure, we chose to use the percentage of discrepancies which included missing answers (discrepant 2) at each wave as the hypothesised misclassification rate.
The authors report "CT imaging generated a higher percentage of discrepancies that were predicted to be clinically significant than plain film radiography, as well as a higher percentage of discrepancies that resulted in immediate changes in management, but the incidence of each remained low overall" [3].
The percentage of discrepancies between CKD-EPI and CKD-EPI mix was intermediate at 5.5%.
For comparison, we masked as 'NNN' additional triplets of nucleotides within the tRNA molecule, and found a higher percentage of discrepancies compared to the anticodon triplet.
However, simulations based on the percentage of discrepancies and missing answers resulted in only a slight decrease in the relative risks towards the null across response wave.
According to the literature, the reported percentage of histological discrepancy in early gastric cancer ranges from 16.3 to 53.7 % [ 21– 25].
The ratios of qSNP/pSNP were calculated to indicate the percentage of nucleotide discrepancies (pSNPs) identified as high-qaality SNPs (qSNPs) by the QualitySNP algorithm.
The percentage of trials with discrepancies between the protocol and the publication will be scored.
From a total of 108 comparisons, the average percentage discrepancy of the scaling natural frequencies was 4.90% with a standard deviation of 6.45%.
Percentage of concordance was calculated, allowing a discrepancy of 0, 1, and 2 days between the registrations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com