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The dependent variable was total direct medical cost per LD patient.
On genotyping platforms, only a few selected index SNPs per LD region are measured.
To accurately quantitate the linkage relationship between neighboring SNPs efficiently, we calculated the number of SNPs per LD block.
Thus, instead of millions of markers, one has just to check one marker per LD block, at least in theory.
Duggal et al. (2008) suggested the simple method of counting 1 SNP per LD block in addition to all the SNPs outside of blocks.
After controlling for other factors, direct medical costs per LD patient in 2000 were lower than those in 1997 (Table 5).
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It was determined considering the number of traits evaluated and the number of independent markers analyzed, which was determined by counting one polymorphism per LD-block plus all interblock polymorphisms [ 91].
The experimental design was a 2×2 factorial with group composition (mixed litters versus littermates) and density (0.15 m2 per pig (HD) versus 0.4 m2 per pig (LD)) as the main factors.
Shaw expression in all tim expressing cells had no gross effects on PER oscillations in LD in peripheral clock cells (Figure 5), nor did it interfere with self-sustained rhythmic PER expression in the DNs (Figure 4).
Although we saw a robust over-expression of Shaw protein in tim-GAL4/UAS-Shaw heads compared to controls (Figure 5B), the relative abundance and phosphorylation state of PER during the LD cycle did not seem to differ between tim-GAL4/UAS-Shaw and control heads (Figure 5A).
The TD library was constructed from 1 μg of TD RNA, as per the LD-PCR protocol of the SMART cDNA library construction kit.
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