Exact(9)
Two types of population will be considered for analysis: per protocol and per intention to treat.
The eradication rate was 38% per intention to treat and 41% per protocol.
The eradication rates were studied per intention to treat and per protocol.
In the AA group, 41 patients were analyzed per intention to treat: 23 received placebo and 18 received nimotuzumab.
All of the patients included in the study were considered for the analysis of per intention to treat.
At this point, 54 patients--59% as per intention to treat and 61% per protocol--were in clinical remission and free of steroids.
Similar(51)
During treatment, illicit heroin use declined drastically among those randomized to injectable diacetylmorphine (from 26.6 to 5.3 days), while days of cocaine use remained stable, as per intention-to-treat (ITT) analysis [ 29].
There was no attrition in one study (Bartha 2005) while six participants were dropped in one study (Park 2011) but both studies conducted the analysis as per intention-to-treat (both assessed as low risk of bias).
Participants who choose not to participate in the intervention continued as initially consented in the natural history observational cohort for 12 months, however their data will be analysed as per intention-to-treat.
This is part of the reason for differences between the per protocol and intention to treat analyses.
The results from the per protocol and intention to treat analysis were similar, and evidence was lacking of a difference in the effect of the intervention between the two age subgroups.
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