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In practice, the genomes started with 1,000 genes, each 1,000 nt long with an error rate in copying DNA of about 10− per errors per nucleotide this is a realistic rate for eukaryotes (Drake 1999).
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On top of this, PER error floor is observed in MCS 14 and 15.
In terms of the PER, error correction significantly improves the reliability, correcting up to 60%% of corrupted packets at −97 dBm.
(d) Per-error correction cycle logical error rate PL as a function of physical error rate p for different code distances.
Thus, high-GC genomes are likely faced with higher per-error product costs as well as process costs.
Indeed, increased per-error costs are often more than counterbalanced by lower predicted error rates owing to more diverse anticodon repertoires in GC-rich genomes.
Some per-patient errors were as high as 17%, but the per-patient error was below 10% for 13 out of 16 patients.
The framework differentiates problems along two independent dimensions: predictability and cost per error.
A higher cost per error requires a higher level of predictability for automation.
We've awarded one point per error: Aston Villa are the worst, having done it 15 times.
Changes in predictability and cost per error can nudge a problem in or out of the robot zone.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com